Hailing Lu, MD, PhD
Research Assistant Professor
Department of Medicine2 hlu@u.washington.edu
My research interest is cancer immunology. The goal of my research is to understand the mechanisms of cancer immunomodulation and to develop novel immunotherapy approaches. We utilize a transgenic mouse model of breast cancer for these studies. Currently I work on a project in collaboration with Bastyr University that studies that immunomodulatory and anti-tumor effect of polysaccharide Krestin (PSK), a mushroom extract. We have found that PSK can stimulate dendritic cells and T cells. Furthermore, gene expression analysis showed that PSK can modulate the tumor microenvironment. The potential effects of PSK on toll-like receptors (TLR) and T regulatory cells are also being investigated. Future research directions include the incorporation of CAM therapy into traditional therapy and develop and a multi-modality therapy for cancer patients.
