Research Studies

Status: Completed
Study area: Nutrition/Dietary, Other
Principal investigator: McCrory MA, Saltzman E, Rolls BJ, Roberts SB
Project period: 2006

The relative effects of energy density and palatability on energy intake, and whether there are familial influences on these effects, are not known.

Status: Completed
Study area: Other
Principal investigator: Messner DJ, Romeo C, Boynton A, Rossie S
Project period: 2006

The microbial toxin okadaic acid (OA) specifically inhibits PPP-type ser/thr protein phosphatases. OA is an established tumor promoter with numerous cellular effects that include p53-mediated cell cycle arrest.

Status: Completed
Study area: Botanical Medicine, Healthy Aging
Principal investigator: Newton KM, Reed SD, LaCroix AZ
Co-investigator(s): Newton KM, Reed SD, LaCroix AZ, Grothaus LC, Ehrlich K, Guiltinan J
Project period: 2006

Black cohosh used in isolation, or as part of a multibotanical regimen, shows little potential as an important therapy for relief of vasomotor symptoms. Clinical Trials Registration number: NCT00169299

Status: Completed
Study area: CAM Research / Education
Principal investigator: Standish, Calabrese, Snider, Kail, Mills, Myers, Traub, and Zwic
Project period: 2006
Status: Completed
Study area: Nutrition/Dietary, General Wellness
Co-investigator(s): Huang TT, Roberts SB, Howarth NC, McCrory MA
Funded by: School of Nutrition and Exercise Science, Bastyr University, 14500 Juanita Dr. NE, Kenmore, WA 98028, USA
Project period: 2005

We present an updated method for identifying physiologically implausible dietary reports by comparing reported energy intake (rEI) with predicted energy requirements (pER), and we examine the impact of excluding these reports.

Status: Completed
Study area: General Wellness
Co-investigator(s): Lara-Castro C, Hunter GR, Lovejoy JC, Gower BA, Fernández JR
Funded by: Department of Nutrition Sciences, University of Alabama, Birmingham, Alabama 35294, USA. larac@uab.edu
Project period: 2005

Genetic variants in the intestinal fatty acid-binding protein-2 (FABP2) gene have been associated with body composition phenotypes.

Status: Completed
Study area: General Wellness
Co-investigator(s): Lara-Castro C, Hunter GR, Lovejoy JC, Gower BA, Fernández JR.
Funded by: Division of Physiology and Metabolism, Department of Nutrition Sciences, University of Alabama, Birmingham, AL 35294, USA. larac@uab.edu
Project period: 2005

To determine the association between the -265 T to C substitution in the apolipoprotein A-II (APOA-II) gene and levels of visceral adipose tissue (VAT) in a group of premenopausal African-American and white women, we genotyped 237 women (115 African-American and 122 white) for this polymorphism.

Status: Completed
Study area: Nutrition/Dietary, General Wellness
Co-investigator(s): Lefevre M, Lovejoy JC, Smith SR, Delany JP, Champagne C, Most MM, Denkins Y, de Jonge L, Rood J, Bray GA
Funded by: Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA. lefevrm@pbrc.edu
Project period: 2005

Trans-fatty acids have been implicated as a risk factor for cardiovascular disease and diabetes. In addition, a polymorphism at codon 54 (Ala54Thr) in the fatty acid-binding protein 2 (FABP2) gene has been suggested to modify an interaction between dietary fat and insulin sensitivity.

Status: Completed
Study area: Nutrition/Dietary, General Wellness
Co-investigator(s): Parks EJ, McCrory MA
Project period: 2005
Status: Completed
Study area: Neurology
Co-investigator(s): Richards TL, Kozak L, Johnson LC, Standish LJ.
Funded by: Department of Radiology, University of Washington, Seattle, WA 98195, USA.
Project period: 2005

 

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