This is a Phase II randomized-placebo controlled trial of a mushroom extract (Trametes versicolor or Tv) in women with early-stage estrogen receptor-negative and progesterone receptor-negative breast cancer who have completed adjuvant radiation therapy.
This observational study examines changes in body composition, energy intake and physical activity in a cohort of 160 perimenopausal women. Annual assessments will be conducted for 7 years to determine the impact of changing reproductive hormone concentrations on body fatness, fat distribution,
A two-year study of 58 participants is planned. This study will test to see if there are benefits for juveniles (6-17) who take the herbal treatment to treat ADHD. Each participant and a parent or guardian will have study visits over a 9-week period.
The aims of this project are to determine which constituents of Spilanthes acmella and Echinacea purpurea have immunomodulatory activity and to assess the importance of synergy in the combined immunomodulatory activity of the two extracts.
The aims of this research project are to assess how Echinacea composition correlates with immunological activities, determine the role of cytochrome P450 metabolism in bioactivity of reportedly active constituents, and investigate whether distinct constituents synergize to enhance bioactivity of
Alkylamides present in Echinacea species have reported immunomodulatory actions, yet their direct effects on T lymphocytes, key mediators of antiviral immunity, are poorly understood.
While no one eating occasion contributes more than any other to excess adiposity, eating more often than three times a day may play a role in overweight and obesity in both younger and older persons. A reduced satiety response to dietary fiber in addition to lower energy expenditure may potentially further contribute to weight gain in older persons.
Of 27 clinical trials testing massage or mind-body interventions, 26 showed significant improvements in symptoms such as anxiety, emotional distress, comfort, nausea and pain. However, results were often inconsistent across studies and there were variations in methodology, so it was difficult to judge the clinical significance of the results.
The relative effects of energy density and palatability on energy intake, and whether there are familial influences on these effects, are not known.
The microbial toxin okadaic acid (OA) specifically inhibits PPP-type ser/thr protein phosphatases. OA is an established tumor promoter with numerous cellular effects that include p53-mediated cell cycle arrest.