This observational study examines changes in body composition, energy intake and physical activity in a cohort of 160 perimenopausal women. Annual assessments will be conducted for 7 years to determine the impact of changing reproductive hormone concentrations on body fatness, fat distribution,
Research Studies
Status: Completed
Study area: Healthy Aging, Chronic Disease
Principal investigator: S Smith (Pennington)
Co-investigator(s): J Lovejoy
Project period: September 2003 - 2007
Status: Completed
Study area: Botanical Medicine, Other
Principal investigator: W Weber
Project period: April 1, 2002 - March 31, 2007
A two-year study of 58 participants is planned. This study will test to see if there are benefits for juveniles (6-17) who take the herbal treatment to treat ADHD. Each participant and a parent or guardian will have study visits over a 9-week period.
Status: Completed
Study area: Botanical Medicine, Immunity
Principal investigator: N Cech
Co-investigator(s): C Wenner
Project period: August 15, 2003 - July 31, 2006
The aims of this project are to determine which constituents of Spilanthes acmella and Echinacea purpurea have immunomodulatory activity and to assess the importance of synergy in the combined immunomodulatory activity of the two extracts.
Status: Completed
Study area: Botanical Medicine, Immunity
Principal investigator: Cynthia Wenner
Funded by: NIH/NCCAM
Project period: September 2000 - July 2006
The aims of this research project are to assess how Echinacea composition correlates with immunological activities, determine the role of cytochrome P450 metabolism in bioactivity of reportedly active constituents, and investigate whether distinct constituents synergize to enhance bioactivity of
Status: Completed
Study area: Botanical Medicine, Immunity
Co-investigator(s): Sasagawa M, Cech NB, Gray DE, Elmer GW, Wenner CA
Project period: 2006
Alkylamides present in Echinacea species have reported immunomodulatory actions, yet their direct effects on T lymphocytes, key mediators of antiviral immunity, are poorly understood.
Status: Completed
Study area: Chronic Disease
Principal investigator: Bradley R, Oberg EB
Project period: 2006
Published in:
Accurate descriptions of naturopathic medicine as a whole system of medical practice are rare in the literature and non-existent for type 2 diabetes.
Status: Completed
Study area: General Wellness
Principal investigator: Herman PM, Sherman KJ, Erro JH, Cherkin DC, Milliman B, Adams LA
Project period: 2006
Published in:
A set of meaningful, measurable treatment criteria based on the naturopathic practice principles were defined that could have generated the majority (82%-93%) of treatment prescriptions given at visits for these conditions. Several of the treatment criteria components are common across the 3 conditions studied, and might be appropriate for all visits to doctors of naturopathy (NDs).
Status: Completed
Study area: Nutrition/Dietary, Healthy Aging, General Wellness
Principal investigator: Howarth NC, Huang TT, Roberts SB, Lin BH, McCrory MA
Project period: 2006
While no one eating occasion contributes more than any other to excess adiposity, eating more often than three times a day may play a role in overweight and obesity in both younger and older persons. A reduced satiety response to dietary fiber in addition to lower energy expenditure may potentially further contribute to weight gain in older persons.
Status: Completed
Study area: CAM Research / Education, Healthy Aging
Principal investigator: Lafferty WE, Downey L, McCarty RL, Standish LJ, Patrick DL
Project period: 2006
Of 27 clinical trials testing massage or mind-body interventions, 26 showed significant improvements in symptoms such as anxiety, emotional distress, comfort, nausea and pain. However, results were often inconsistent across studies and there were variations in methodology, so it was difficult to judge the clinical significance of the results.
A twin study of the effects of energy density and palatability on energy intake of individual foods.
Status: Completed
Study area: Nutrition/Dietary, Other
Principal investigator: McCrory MA, Saltzman E, Rolls BJ, Roberts SB
Project period: 2006
Published in:
The relative effects of energy density and palatability on energy intake, and whether there are familial influences on these effects, are not known.