Research Studies

Status: Completed
Study area: Chronic Disease
Principal investigator: McCarty RL, Weber W, Loots B, Breuner CC, Vander Stoep A, Manhar

CAM diets were associated with increased quality of life in youth with diabetes, whereas supplement use and stress-reduction activities were associated with decreased quality of life. The temporal sequence between CAM use and quality of life requires further study.

Status: Completed
Study area: CAM Research / Education
Principal investigator: M Heitkemper
Co-investigator(s): Timothy Callahan, PhD
Project period: 2002 – 2009

The primary purpose was to enhance the integration of information about CAM therapies into UW health sciences curricula, specifically the required undergraduate nursing didactic and clinical courses, and by increasing the nursing faculty's understanding of CAM.

Status: Completed
Study area: CAM Research / Education
Principal investigator: Leanna Standish, PhD
Project period: 2003-2005

This project was designed to bring together naturopathic physicians and conventional research scientists to establish the Naturopathic Medical Research Agenda workgroup. It highlights the use of a prioritization criteria to determine the specific focus of future research efforts.

Status: Recruiting
Study area: Neurology
Principal investigator: Laurie Mischley, ND
Funded by: Barbara Wright Multiple Sclerosis Research Fund
Project period: 10/17/12-2/28/12

This case-control study will recruit individuals with a diagnosis of MS and healthy controls. Individuals will be asked to come to Bastyr Clinical Research Center for a single study visit, at which time dietary intake, current medications and supplements, other medical diagnoses, and coagulation will be evaluated.

Status: Completed
Study area: Oncology
Principal investigator: Cynthia Wenner, PhD
Project period: 2008 – 2011

The objective of this study is to better understand the mechanisms of polysaccharide krestin, an extract of mushroom Trametes versicolor, enhancement of docetaxel for the treatment of hormone refractory prostate cancer (HRPC) to lay the groundwork for a Phase I dose escalation trial in p

Status: Completed
Study area: Oncology
Principal investigator: Mary Disis (UW)
Co-investigator(s): Cynthia Wenner, PhD
Project period: 2007 – 2011

Mushroom extracts have long been used in Asia as immunopotentiating agents. Previous studies have shown that ingestion of mushroom extracts can cause tumors to shrink or stop progressing in animal models of cancer and in cancer patients.

Status: Completed
Study area: Botanical Medicine, Immunity
Principal investigator: James Taylor (UW)
Co-investigator(s): Cynthia Wenner, PhD
Project period: 2006 – 2011

An unexpected result of an earlier randomized controlled trial was that patients receiving Echinacea had fewer subsequent upper respiratory infections (URIs) during the four-month study period than children who received placebo for treatment of acute symptoms.

Status: Completed
Study area: Immunity, Oncology
Principal investigator: Cynthia Wenner, PhD
Project period: October 2005 - August 2010

This diversity supplement project is designed to provide research training to Lisa Price ND, under mentorship of Cynthia Wenner, PhD. Dr. Price is studying the modulatory effects of Trametes versicolor on T helper 1 and T helper 2 phenotypic expression in healthy individuals as a substudy that is integral to the first aim of the parent Project 2 that is part of the Developmental Center for Research on CAM.

Status: Completed
Study area: Nutrition/Dietary, Chronic Disease
Principal investigator: Ryan Bradley, ND
Funded by: Standard Process Inc.
Project period: 2009-2010

This project will evaluate the effects of carotenoid enrichment from food and supplements in healthy volunteers.

Status: Completed
Study area: Immunity, Oncology
Principal investigator: J Slaton (U of MN)
Co-investigator(s): Cynthia Wenner, PhD
Project period: 2004 – 2010

The objectives of this developmental center grant are 1) developing basic, translational, and clinical research to explore the feasibility and scientific rationale for use of mushroom extracts as immunopotentiating agents; 2) facilitating the development of the capacity of investigators at Bastyr University to participate in basic and translational CAM research; 3) enhancing the capacity of investigators at the University of Minnesota to participate in translational and clinical CAM research.

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