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Kaleb C. Lund, PhD
- Core Faculty, School of Naturopathic Medicine, Department of Botanical Medicine
- Assistant Research Scientist, Bastyr University Research Institute
Dr. Lund is currently teaching classes through the departments of Botanical Medicine and Basic Sciences. His focus is on botanical research, phytochemistry/pharmacy and dietary supplement quality and regulations. His research interests include developing models to improve the validity of in vitro assessment of botanical medicines including simulated digestion and hepatic metabolism as well as analytical methods that account for the complexity of whole herbal products. Dr. Lund continues to mentor graduate and undergraduate students in a multitude of exciting and creative research projects developed by students in the herbal science and nutrition programs.
- BS in biochemistry from University of Minnesota in 2000
- MS in chemistry from University of Minnesota in 2004
- PhD in toxicology from University of Minnesota in 2007
- Postdoctoral training in herbal science at Bastyr University in 2010
Dr. Lund’s graduate research focused on mitochondrial toxicity of pharmaceuticals — studying the effects of anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) on mitochondrial respiration, gene expression and energy signaling.
As a postdoctoral fellow in the Bastyr University Research Institute (BURI), Dr. Lund expanded his research interests to include herbal science research, including the preparation, authentication and assessment of the biological activities of botanical medicines. His postdoctoral research involved the study of how excess glucose leads to mitochondrial dysfunction using in vitro models of hyperglycemia-induced endothelial dysfunction. This research demonstrated that an extract of Japanese dogwood fruit (Cornus officinalis) prevents NF-κB activation and protects mitochondria from hyperpolarization caused by excess glucose.
More recently Dr. Lund served as the Director of Research Laboratories at BURI for three years, managing and maintaining an active, multi-study, natural products research laboratory. He worked to expand the analytical and basic science research capabilities of Bastyr University and strived to keep active projects running smoothly. During this time Dr. Lund mentored 18 undergraduate and graduate student research projects ranging from the immunomodulatory effects of Devil’s Club (Oplopanax horridus) to the discovery of reserpine in Crossvine (Bignonia capreolata). Additionally, using an industry funded grant, he established a method for modeling in vitro intestinal absorption and applied it to combinations of quercetin, curcumin and resveratrol.
Undergraduate-level: Research Methods for Herbal Science, Test Methods for Botanical Authentication, QA/QC for Herbal Science, Pharmacognosy, Pharmacology Overview for Herbal Science, Research Applications in Herbal Science and General Chemistry I & II.
Graduate-level: Clinical Pharmacognosy, Natural Products and Intestinal Microbiota.
Dr. Lund’s interests include mitochondrial bioenergetics, inflammatory and immune modulation by botanicals, improving the models of in vitro herbal assessment to decrease the use of animal models and the analytical examination of botanicals to demonstrate chemical diversity within species. His dream is to develop methods that account for the complex and emergent pharmacology of botanical medicines.
Dr. Lund is a clinical herbalist and magical philosopher interested in the interaction of the human organism with plants and the natural world at the chemical/physiological, emotional and spiritual levels. He is particularly interested in the process in which plants facilitate healing through biochemistry, emotional connectedness and ultimately through consciousness. Dr. Lund enjoys reading (and putting into practice) classical texts on herbalism and western mystery traditions, especially the integration of astrology and herbal medicine.
Dr. Lund believes that the return to health involves the integration of the self into the ecosystem – specifically the realization that you are an integrated part of your environment and that disease represents the separation of our consciousness self with our organism or environment.
When teaching in the classroom or laboratory, Dr. Lund tries to facilitate personal ownership of knowledge by encouraging the individual’s flow of insights and mistakes in an environment free of judgment.